Ceramide
Description
Ceramides – Active Lipid Concentrate
Ceramides is a lipid blend designed for repairing and restructuring the skin barrier. It is a concentrated solution delivering 10% Ceramide NP optimally solubilized in a fatty alcohol base. This active ingredient is recommended in formulations to rebuild the intercellular lipid structure, reducing water loss and increasing the resistance of the stratum corneum. It directly intervenes in regenerating the protective lipid layer, preventing chronic skin dehydration and repairing structural damage to the hair fiber.
Ingredients (INCI): Isocetyl Alcohol, Cetyl Alcohol, Ceramide NP.
Technical Characteristics
- Appearance: Off-white to yellowish paste with a neutral odor.
- Solubility: Soluble in lipid phases upon heating.
- Quality: High-purity biomimetic active ingredient, vegan, produced through patented biofermentation processes.
- Indicative Dosage: 0.25% - 5%
Efficacy Studies and Clinical Data
Product performance on skin and hair tissue is demonstrated through clinical tests conducted by the manufacturer:
- Increased Water Retention Capacity (In Vivo): In a 7-day clinical study, applying formulas containing 0.05% and 0.5% Ceramides to the forearms of volunteers resulted in a statistically significant increase in skin hydration (measured via corneometry) compared to the control product.
- Long-Term Sustained Hydration Effect: Following complete cessation of treatment on day 7, areas treated with the control product showed a rapid drop in water levels. In contrast, areas treated with the 0.5% Ceramides formula maintained high and sustained hydration levels for an additional 6 days after the last application (up to day 13 of monitoring).
- Protection Against Chemical Irritation and TEWL Reduction: Volunteers' skin treated for 7 days with formulas containing 0.2% and 0.5% Ceramides was exposed to a chemical challenge using an aqueous 5% Sodium Dodecyl Sulphate solution for 2 hours. Measurements demonstrated that areas protected with Ceramides exhibited a significantly smaller increase in transepidermal water loss (TEWL) compared to the control area, confirming the reinforcement of the skin barrier. Furthermore, tests on healthy skin showed that the active does not block pores and does not disrupt normal skin physiology (non-occlusive action).
- Restoration of Mechanical Strength in Hair (Ex Vivo): On virgin hair tresses structurally damaged by repeated perming and bleaching processes, 10 wash cycles (using 8% SLES) were applied, followed by a rinse-off conditioner containing 0.5% Ceramides. Tensile strength tests demonstrated that the Ceramides treatment restored approximately 35% of the break stress lost due to chemical degradation.
Main Properties
- Lipid Barrier Restructuring: Delivers Ceramide NP directly into the extracellular matrix of the stratum corneum, replenishing lipid deficits induced by aging or environmental stressors.
- High-Compatibility Matrix: Solubilizing the ceramide in fatty alcohols ensures superior bioavailability and rapid integration, providing deep emolliency.
- Reduction of Water Loss (Anti-TEWL): Forms a non-occlusive, hydrophobic protective barrier that locks in water evaporation from deeper epidermal layers.
- Long-Lasting Hydration: Maintains a high water-binding capacity within the epidermis even several days after stopping application.
- Protection Against Surfactants: Limits intercellular cement degradation caused by harsh detergents or soaps.
- Hair Structural Repair: Restores strength, vitality, shine, and combability to damaged or chemically treated hair.
Applications
- Nourishing day and night facial creams intended for dry, mature, sensitive, or barrier-compromised skin.
- Anhydrous treatments and restorative lipid elixirs.
- Balms for restoring extremely dry or cracked skin areas (hands, elbows, heels).
- Dermatocosmetic barrier formulations, winter creams, environmental protection products.
- Post-aesthetic procedure care products requiring rapid epidermal restoration.
- Hair care products: conditioners, leave-in treatments, and conditioning shampoos.
Formulation Guide
- Procedure: Add to the oil phase and heat up to 85°C; it is crucial that it dissolves completely. Incomplete dissolution will generate isolated micro-crystals that reduce the efficacy of the finished product.
- Stability, Compatibility: Compatible with most common cosmetic ingredients; stable across a wide pH range, optimal between 4.0 - 8.0.
Safety in Use and Storage
Safety Profile: High-purity active ingredient, non-irritating. Its components are classified as safe for cosmetic use, featuring optimal skin tolerance.
Precautions: For external cosmetic use only.
Storage: Keep the product in its closed container, in a dry and cool place, protected from direct sunlight.
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