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OrniFill

[42]
5.50 (VAT included) 6.88
4.62 (without VAT)
_ _
Code Size Net price Total price Quantity
M-1474 10 g
4.62
5.50
6.88
M-1474-0.25 250 g
91.63
109.04
Product reference D-1474

Description

OrniFill - Encapsulated Technology for a Plumped Appearance

OrniFill is a modern biotechnological active ingredient awarded the Gold Award at In-Cosmetics. It is based on the amino acid L-ornithine encapsulated within an innovative delivery system (Ionosome™), designed to contribute to a visibly plumper appearance in areas prone to volume loss as skin ages.

Subcutaneous adipose tissue is naturally responsible for the full appearance of the face. With age, this layer progressively decreases, which contributes to the emergence of more visible nasolabial folds, a sagging look along the lower jawline, and hollows under the eyes. According to studies conducted by the supplier of this active, OrniFill contributes to a visibly improved appearance in these areas through a non-invasive, topically applied method.

Former cosmetic name of this ingredient: Dermo-Filler


Ingredients: Water, Propanediol, Ornithine, Phospholipids, Glycolipids.


Characteristics

  • Appearance: Off-white, cloudy liquid with a faint characteristic odor.
  • Technology: L-ornithine encapsulated in Ionosome™ for optimal and targeted penetration.
  • Mechanism of Action: The active was studied by the manufacturer in relation to natural adipose tissue processes at the cellular level. These mechanisms were documented in in vitro/ex vivo studies conducted by the supplier on the purified active ingredient - they do not represent a direct claim on body functions following application of the finished product.
  • Origin: 100% natural origin, sustainable, biotechnological.

Manufacturer's Studies

According to technical documentation provided by the supplier of this active, in vivo tests conducted showed:

  • Nasolabial Fold Appearance: The application of 2% active ingredient in a test cream was associated, in the supplier's study, with a reduction in visible wrinkle depth of up to 37% after 30 days.
  • Cheekbone Appearance: Volunteers in the supplier's study reported a perception of more visible facial volume and a firmer look after 2 months of use.
  • Texture Appearance: The level of perceived skin roughness decreased by 27.5% in the supplier's study, with a smoother and more even look reported by subjects.
  • Self-Assessment: Subjects reported, in proportions ranging between 70-90%, an improved perception of smoothness, firmness, rested appearance, and facial contours.

Note: The data above originates from studies conducted by the supplier on this ingredient in its proprietary test formulation at the specified concentration. OrniFill is this ingredient in its pure, unmodified form. Results obtained in a finished cosmetic product will depend on the concentration used and the overall formula into which it is incorporated by the user.


Main Properties

  • Plumping Appearance: According to supplier studies, it contributes to a visibly plumper appearance in areas prone to volume loss, particularly in the cheeks, nasolabial folds, and deep dark circles.
  • Wrinkle Appearance: Contributes to a visibly smoother appearance of wrinkles, according to data provided by the supplier.
  • Visual Anti-Aging: Targets the global appearance of mature skin, not merely surface texture.
  • Contour Appearance: Helps provide a more defined appearance to facial contours.
  • Hydration and Protection: The matrix of phospholipids and glycolipids contributes to a feeling of skin barrier comfort and hydration maintenance.

Usage Recommendations

General recommended dosage: 0.5% - 2%.
For a more visible effect in intensive care formulations, a 2% concentration is recommended. For daily maintenance products, a dosage of 0.5% - 1% is sufficient.

Applications

  • Serums and day/night creams for mature skin (intensive anti-aging care)
  • Eye contour serums, creams, and targeted treatments
  • Targeted treatments for the nasolabial fold area
  • Creams for a plumper appearance of the cheekbones and bust
  • Products for a plumping look along lip contours
  • Hand creams for a revitalized appearance on the back of the hands

Formulation Guide

  • Procedure: Preferably add during the final phase of preparation.
  • Temperature: Incorporation at temperatures below 40°C is recommended to preserve the integrity of the Ionosomes.
  • pH Range: Optimal within a pH range between 4.5 and 6.0.
  • Technical Tip: Avoid prolonged high shear forces after adding the active ingredient to prevent damage to the delivery capsules.

Frequently Asked Questions (FAQ)

How does OrniFill differ from Hyaluronic Acid?
Hyaluronic acid retains water in the dermis, providing temporary hydration and visible plumping. According to supplier studies, OrniFill operates via a different mechanism of action at the purified active level, which was associated in its tests with a more stable plumping appearance over time.

Can it be used on the entire body?
Yes, it is a suitable ingredient for formulations targeting areas where loss of volume appearance is visible, such as the hands, neck, or decolleté.

When do results start to show?
According to supplier studies on the purified active ingredient, the first signs of smoothing appeared after approximately 4 weeks of use, while the maximum plumping appearance was observed after 60 days of daily use in that study.


Usage Safety

Profile: Safe ingredient, well-tolerated by the skin.
Precautions: Intended exclusively for cosmetic use. Do not ingest. Avoid direct contact with the eyes.
Storage: Store in the original packaging in a cool place (preferably 15-25°C), protected from light and moisture.

Bibliography and Sources

Technical documentation and information provided by the supplier.
CosIng - European Commission Database for Cosmetic Substances and Ingredients.
International regulations on cosmetic ingredients.
Regulation (EC) No 1223/2009 on cosmetic products.


Details

Code
D-1474
Categories
Other names
Adipofill`in™
Key benefits
anti-aging, anti-wrinkle, densifying, skin tonic
Specific indications
dark circles, stretch marks, wrinkles, fine lines
Skin care
Eye Creams, Face creams, Serums, Treatments
Skin type
All types, Mature
Body care
Creams Emulsions
Solubility
in water
Use level
0.5 - 2.0 %
Storage
in a cool dry place away from direct sunlight
Download
TDS  |  MSDS

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Reviews

4.9 out of 5 stars
Based on 42 votes
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E
Elena L.
10 Feb 2025
Hello, can you add this product directly into the cream or serum that I use, I mean a commercially bought cream, it is not prepared by me.
G
Gabriela P.
10 Jan 2025
I use this cosmetic active in the preparation of my day cream, which I keep adapting with new ingredients. I appreciate its properties, which lead to a fuller, younger-looking face and reduce dark circles.
M
Mihaela C.
10 Jan 2025
Excellent A cosmetic active that has instant effect! Of course combined with other ingredients. I use it especially in face creams but also in serums. Thanks!
L
Liliana T.
10 Dec 2024
Not missing from anti-wrinkle serums. I really seem to notice a difference in nasolabial folds since using Dermo-filler
I
Ilinca r.
10 Dec 2024
Very good. I use it in my anti-wrinkle cream. The effect is visible. It reduces fine wrinkles, the skin is smoother.
C
Cosmina C.
10 Dec 2024
Too strong for dark circles and wrinkles. I made the peptide eye serum recipe, my dark circles were visibly reduced.
S
Sidenco R.
10 Dec 2024
An active whose presentation sounds very promising, top-notch; I still can't say that I've noticed very visible effects but I rely on it and I keep insisting, keep waiting for it to appear.
C
Claudiu B.
10 Dec 2024
I received a bottle of this active as a gift, I didn't even know it existed. Now it's a must in anti-wrinkle creams. I highly recommend it!
M
Miki M.
10 Dec 2024
Wonderful.I have used it in my face cream and in a serum ,you quickly notice a difference.I always had deep wrinkles on my forehead ,which have reduced.
A
Adriana U.
10 Dec 2024
Dermo-filler is able to increase the volume of fatty tissue for a lipofilling-like effect, but through a non-invasive method.
C
Carciumaru C.
10 Dec 2024
Dermo-filler is an excellent product with a visible and immediate effect. A key ingredient for an anti-aging product with multiple benefits.
M
Mihaela C.
10 Oct 2024
A cosmetic active that works instantly! Of course combined with other ingredients. I use it especially in face creams but also in serums. Thank you!
A
Adriana M.
10 Oct 2024
This product is particularly effective if applied daily. With persistence and ambition skin cells can become full of vitality and fine lines are visibly reduced. Recommendation.
A
Angela n.
10 Oct 2024
maybe because of it I don't have too many wrinkles? :) a very useful product if you want a complexion without problems and without wrinkles.
E
Emanuela G.
10 Oct 2024
It is an excellent product for mature wrinkles both around the eyes and face. I use it in 2% concentration and it does not affect the stability of emulsions.
C
Cristina M.
10 Oct 2024
I use it in my face serums , namely global anti -aging booster, antiaging creams, lift-fill cream , with great results.I recommend with confidence.
E
Eva B.
10 Oct 2024
Dermo-filler is an essential active in my serums, it is easy to work with and the results are visible.
L
Luciana S.
22 May 2024
To be honest, I haven't seen any of the proposed effects of this product. I've been using it for years around my eyes and I don't see that plumping effect .
A
Alexa M.
22 May 2024
Since using dermo-filler, the look of my complexion is much younger and even firmer, so I recommend for a rejuvenated look!
V
Villy T.
22 May 2024
A must in my anti-wrinkle serum with peptides and city guard. A powerful anti-wrinkle effect.