Name: Astaxanthin Hy-Active
SKU: D-1801

Description

Astaxanthin Hy-Active is a bio-active cosmetic ingredient obtained using cellular water extracted from the red algae Haematococcus pluvialis and fermented yeast extract Phaffia rhodozyma. This complex is rich in powerful antioxidants, especially astaxanthin, and is designed to combat the process of "inflammaging" - skin aging caused by chronic inflammation. The product acts by reducing inflammatory mediators and maintaining cell viability, offering superior protection against collagen degradation and the appearance of fine lines.

Phaffia rhodozyma and Haematococcus pluvialis are known as microorganisms capable of synthesizing the carotenoid astaxanthin. Astaxanthin is known for improving skin condition and reducing inflammation. Astaxanthin Hy-Active utilizes a new approach to sustainability, leveraging the presence of astaxanthin from red algae and fermented yeast to rejuvenate the complexion with powerful anti-inflammatory benefits.

Tests and Clinical Studies

The efficacy of the Astaxanthin Hy-Active ingredient has been demonstrated through in vitro studies on human dermal fibroblasts.

Reduction of inflammation (IL-6): In an induced inflammatory environment (with LPS), treatment with this ingredient reduced IL-6 levels by 97% at a concentration of 1.0%. The anti-inflammatory effect was superior to that of Dexamethasone at similar concentrations.
Cell viability: Viability tests confirmed that the ingredient presents no cytotoxic effects and does not inhibit cell viability at the tested concentrations, supporting healthy mitochondrial metabolism.

Ingredients: Haematococcus Pluvialis Extract, Yeast Ferment Extract, Lactobacillus Ferment

Characteristics

Solubility: Water-soluble, miscible in aqueous media and emulsions.
Dosage: 1% - 10%, with clinically proven efficacy starting from 1%.
Appearance: Slightly cloudy liquid, orange, semi-viscous.
Quality: Natural, vegan, non-GMO, sustainable, without classic preservatives (contains Lactobacillus Ferment as an antimicrobial agent).
Origin: Red algae and yeast (fermentation).
Testing method: ELISA for IL-6, Resazurin cell viability assay.

Main Properties

Powerful anti-inflammatory: Significantly reduces levels of Interleukin-6 (IL-6), a pro-inflammatory marker associated with aging and skin matrix degradation.
Nutritive, soothing, promotes a beneficial isotonic environment for optimal skin health.
Anti-aging protection: By inhibiting the NF-kB pathway and IL-6 production, it helps prevent the degradation of collagen and the extracellular matrix, diminishing wrinkle formation.
Cellular vitality: Maintains the metabolic activity of fibroblasts and ATP production, ensuring optimal functioning and health of dermal cells.

Usage Recommendations

It is suitable as an ingredient for preparing products intended for preventing signs of skin aging, hydrating, and soothing sensitive skin.

It can be integrated into formulations for sensitive or irritated scalps.

Recommended for care products after exposure to the sun or stress factors.

Applications

Well-aging and anti-aging serums and creams, anti-wrinkle and collagen protection.
Products for sensitive or irritated skin, due to the ability to reduce inflammatory markers.
Hydrating and revitalizing facial toners and essences.
Scalp tonics, to reduce inflammation and support follicle health.
Gentle shampoos with a soothing effect.
After-Sun products to soothe inflammation caused by UV radiation.
Hydrating, nutritive, anti-aging body lotions and creams.

Formulation Guide

Recommended dosage: 1-10%

Procedure: Add to the aqueous phase of formulas.

Stability: Can be heated, stable up to 80°C. Optimal pH value: 4.0 - 8.0

Frequently Asked Questions (FAQ)

How does it act on aging?
By reducing IL-6, the ingredient interrupts the NF-kB signaling pathway that leads to the production of metalloproteinases (MMP-1), enzymes responsible for the degradation of collagen and elastin.

Is it safe for the skin?
Yes, cell viability studies have shown that it does not negatively affect cellular metabolism and is not cytotoxic at normal usage concentrations.

What is astaxanthin?
Astaxanthin is a powerful carotenoid extracted from the algae Haematococcus pluvialis, known for its superior antioxidant properties.

Safety in Use

Product intended exclusively for cosmetic use. Keep out of reach of children.

In vitro tests on human dermal fibroblasts demonstrated that the ingredient does not induce cytotoxicity and maintains a healthy cellular metabolism, indicating ample ATP production.

Storage: Store in a dry and cool place, protected from direct sunlight. Close the container tightly after use.