Formula: CB8802 Difficulty level: beginner Shelf life: min 6 months pH optimal: 5.5-6.0 Phase Ingredients Quantity A Lotion Base Organic 100 ml A Hyaluronic acid LMW 0,5 gr A Pomegranate oil 2 gr A...
Dermo-filler
€6.88
(VAT included)
€5.78
(without VAT)
_ _
Description
Dermo-filler - Rejuvenation through Lipo-structure and Non-Invasive Alternative to Lipofilling
Dermo-filler is a state-of-the-art biotechnological active ingredient, awarded the gold prize at In-Cosmetics, designed to combat the structural aging process. Based on the amino acid L-ornithine encapsulated in an innovative delivery system (Ionosome™), this active works by stimulating adipocytes (fat cells) to increase the volume of subcutaneous adipose tissue. The effect is one of global rejuvenation: deep wrinkles are "filled" from the inside, cheekbones regain a more voluminous appearance, and the face contour becomes remodeled.
Subcutaneous adipose tissue is responsible for the full appearance of the face. With age, the fat layer progressively decreases, leading to the appearance of deep nasolabial folds, sagging skin in the lower jaw area, and hollows under the eyes. Dermo-filler is capable of increasing the volume of fatty tissue for an effect similar to lipofilling, but through a non-invasive method.
Ingredients: Water, Propanediol, Ornithine, Phospholipids, Glycolipids.
Characteristics
- Presentation: Cloudy whitish liquid with a weak characteristic odor.
- Technology: L-ornithine encapsulated in Ionosome™ for deep and targeted penetration.
- Mechanism of action: Stimulates lipohormesis (adipose tissue growth) by activating the PLIN1 enzyme and inhibiting lipolysis.
- Origin: 100% natural origin, sustainable, biotechnological.
Tests and Clinical Studies
The performance of Dermo-filler has been demonstrated through rigorous in vivo clinical studies:
- Nasolabial fold appearance: The application of 2% active in a cream generated a reduction in wrinkle depth by up to 37% after 30 days.
- Cheekbone Remodeling: Volunteers reported a visible increase in facial volume and an improvement in firmness after just 2 months of use.
- Anti-Roughness Effect: The skin roughness level decreased by 27.5%, offering a much smoother and more uniform texture.
- Self-Assessment Test: volunteers agree that it provides smoother skin (90% positive opinions), firmer (90% positive opinions), less tired (90% positive opinions), firmer (80% positive opinions), more lifted (75% positive opinions), lip contour is smoother (70% positive opinions).
Main Properties
- Filler Effect: Regenerates volume lost with age, especially in the area of the cheeks and nasolabial folds, and deep dark circles (hollows). Induces the refilling of fat cells and increases adipose tissue volume to mimic lipofilling results.
- Wrinkle Filling: Acts mechanically and biologically to push the wrinkle from the inside out through the expansion of adipose tissue.
- Structural Anti-Aging: Targets the cause of deteriorating facial features, not just the symptoms on the skin surface.
- Contour Remodeling: Helps redefine the "triangle of youth," lifting sagging tissues.
- Hydration and Protection: The matrix of phospholipids and glycolipids helps restore the skin barrier and maintain hydration.
Usage Recommendations
General recommended dosage: 0.5% - 2%.
For visible results in professional anti-aging treatments, usage at a 2% concentration is recommended. For maintenance and prevention products, a dosage of 0.5% - 1% is sufficient.
Applications
- Serums and day/night creams for mature skin (intense anti-aging).
- Serums, creams, and treatments for the eye contour.
- Targeted treatments for nasolabial folds and the nasolabial area.
- Creams for volumizing cheekbones and the bust.
- "Plumping" products for the lip contour.
- Hand creams for rejuvenation, with a focus on restoring volume on the back of the hand.
Formulation Guide
- Procedure: Preferably add in the final phase of preparation.
- Temperature: Incorporation at temperatures below 40°C is recommended to preserve the integrity of the Ionosomes.
- pH Range: Optimal within a pH range of 4.5 to 6.0.
- Technical tip: Avoid prolonged high shear forces after adding the active to prevent breaking the delivery capsules.
Frequently Asked Questions (FAQ)
How does Dermo-filler differ from Hyaluronic Acid?
Hyaluronic acid retains water in the dermis, offering temporary hydration and filling. Dermo-filler acts at a deeper level, stimulating the growth of natural fatty tissue, providing a more stable and long-term volumizing result.
Can it be used on the whole body?
Yes, it is excellent for areas where the loss of adipose volume is visible, such as the hands, neck, or even the décolleté.
When do results start to show?
The first signs of smoothing appear after about 4 weeks, but the maximum structural volumizing effect is visible after 60 days of daily use.
Safety in Use
Profile: Safe ingredient, well tolerated by the skin.
Precautions: Intended exclusively for cosmetic use. Keep out of reach of children. Do not ingest. Avoid direct contact with eyes.
Storage: Store in the original packaging, in a cool place (preferably 15-25°C), protected from light and moisture.
Bibliography and Sources
Documentation and technical information provided by the Manufacturer.
CosIng - European Commission Database for Cosmetic Substances and Ingredients.
International regulations regarding cosmetic ingredients.
Regulation (EC) No. 1223/2009 on cosmetic products.
Details
Code
D-1474
Categories
Odor, Aroma
faint characteristic
INCI
Water, Propanediol, Ornithine, Phospholipids, Glycolipids
Other names
Adipofill`in™
Appearance
liquid, white, yellowish
Method of production
biotechnology, fermentation
Key benefits
anti-aging, anti-wrinkle, densifying, skin tonic
Specific indications
dark circles, stretch marks, wrinkles, fine lines
Skin care
Eye Creams, Face creams, Serums, Treatments
Skin type
All types, Mature
Body care
Creams Emulsions
Solubility
in water
Use level
0.5 - 2.0 %
Storage
in a cool dry place away from direct sunlight
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Reviews
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E
Elena Laura F.
10 Feb 2025
Hello, can you add this product directly into the cream or serum that I use, I mean a commercially bought cream, it is not prepared by me.
G
Gabriela P.
10 Jan 2025
I use this cosmetic active in the preparation of my day cream, which I keep adapting with new ingredients. I appreciate its properties, which lead to a fuller, younger-looking face and reduce dark circles.
M
Mihaela Cerasela N.
10 Jan 2025
Excellent A cosmetic active that has instant effect! Of course combined with other ingredients. I use it especially in face creams but also in serums. Thanks!
L
Liliana T.
10 Dec 2024
Not missing from anti-wrinkle serums. I really seem to notice a difference in nasolabial folds since using Dermo-filler
I
Ilinca r.
10 Dec 2024
Very good. I use it in my anti-wrinkle cream. The effect is visible. It reduces fine wrinkles, the skin is smoother.
C
Cosmina C.
10 Dec 2024
Too strong for dark circles and wrinkles. I made the peptide eye serum recipe, my dark circles were visibly reduced.
S
Sidenco R.
10 Dec 2024
An active whose presentation sounds very promising, top-notch; I still can't say that I've noticed very visible effects but I rely on it and I keep insisting, keep waiting for it to appear.
C
Claudiu B.
10 Dec 2024
I received a bottle of this active as a gift, I didn't even know it existed. Now it's a must in anti-wrinkle creams. I highly recommend it!
M
Miki M.
10 Dec 2024
Wonderful.I have used it in my face cream and in a serum ,you quickly notice a difference.I always had deep wrinkles on my forehead ,which have reduced.
A
Adriana U.
10 Dec 2024
Dermo-filler is able to increase the volume of fatty tissue for a lipofilling-like effect, but through a non-invasive method.
C
Carciumaru C.
10 Dec 2024
Dermo-filler is an excellent product with a visible and immediate effect. A key ingredient for an anti-aging product with multiple benefits.
M
Mihaela Cerasela N.
10 Oct 2024
A cosmetic active that works instantly! Of course combined with other ingredients. I use it especially in face creams but also in serums. Thank you!
A
Adriana Monica T.
10 Oct 2024
This product is particularly effective if applied daily. With persistence and ambition skin cells can become full of vitality and fine lines are visibly reduced. Recommendation.
A
Angela n.
10 Oct 2024
maybe because of it I don't have too many wrinkles? :) a very useful product if you want a complexion without problems and without wrinkles.
E
Emanuela G.
10 Oct 2024
It is an excellent product for mature wrinkles both around the eyes and face. I use it in 2% concentration and it does not affect the stability of emulsions.
C
Cristina M.
10 Oct 2024
I use it in my face serums , namely global anti -aging booster, antiaging creams, lift-fill cream , with great results.I recommend with confidence.
E
Eva B.
10 Oct 2024
Dermo-filler is an essential active in my serums, it is easy to work with and the results are visible.
L
Luciana S.
22 May 2024
To be honest, I haven't seen any of the proposed effects of this product. I've been using it for years around my eyes and I don't see that plumping effect .
A
Alexa M.
22 May 2024
Since using dermo-filler, the look of my complexion is much younger and even firmer, so I recommend for a rejuvenated look!
V
Villy T.
22 May 2024
A must in my anti-wrinkle serum with peptides and city guard. A powerful anti-wrinkle effect.