Gluconolactone

[11]
3.72 (VAT included)
3.13 (without VAT)
_ _
Code Size Net price Total price Quantity
M-1478-0.1 100 g
3.13
3.72
M-1478-1 1 kg
11.52
13.71
M-1478-5 5 kg
38.71
46.07
Product reference D-1478

Description

Gluconolactone - Gentle Exfoliation, Intense Hydration, and Antioxidant Protection

Gluconolactone is a naturally derived polyhydroxy acid (PHA), obtained through the oxidation of glucose, and is considered the gentle successor to traditional AHA acids. Due to its larger molecular structure, it penetrates the skin gradually, offering effective exfoliation without the stinging sensation or redness. In addition to its role in cellular renewal, gluconolactone acts as a powerful humectant and a natural antioxidant, being one of the few exfoliating ingredients recommended even for very sensitive, reactive, or rosacea-prone skin.


Ingredients (INCI): Gluconolactone.


Technical Characteristics

  • Nature: Pure polyhydroxy acid (PHA), in the form of a white crystalline powder.
  • Solubility: Completely water-soluble.
  • Mechanism: Chemical exfoliation by weakening the bonds between the dead cells of the epidermis (corneocytes).
  • Functions: Exfoliant, humectant (attracts water), chelator (captures heavy metals), antioxidant.

Information from Specialized Literature

Gluconolactone is documented in aesthetic dermatology for its multiple benefits that go beyond simple exfoliation:

  • Superior Tolerance: Clinical studies indicate that PHA has a much lower irritation potential than AHA acids, making it suitable for individuals with a fragile skin barrier.
  • Antioxidant Support: Research demonstrates that gluconolactone has the capacity to neutralize free radicals, protecting the skin against the harmful effects of UV radiation (without increasing skin photosensitivity as much as other acids).
  • Hydration and Barrier: Specialized literature highlights its role in strengthening the skin's protective barrier, reducing transepidermal water loss (TEWL).
  • Anti-acne Action: Comparative tests have shown that gluconolactone is effective in reducing imperfections in acne-prone skin, with efficacy comparable to some classic therapeutic agents, but with fewer side effects.

Potential Properties

  • Texture Refining: Eliminates dead cells, leaving the complexion smooth, radiant, and uniform.
  • Gentle Anti-Aging: Helps diminish fine lines and superficial pigmentation spots by accelerating cellular turnover.
  • Deep Hydration: Due to its multiple hydroxyl groups, it retains water in the upper layers of the skin.
  • Stabilizer and Chelator: Improves the stability of cosmetic products by capturing metal ions that can oxidize the formula.

Usage Recommendations

General recommended dosage: 1% - 5%.
In toners, lotions, cleansers, and daily creams: 1% - 5%.
In intensive exfoliation products (peels): up to 15%.

Applications

  • Exfoliating serums and lotions for sensitive or dry skin.
  • Anti-aging creams for evening out skin tone.
  • Care products for skin prone to imperfections and dilated pores.
  • After-sun or urban protection products due to its antioxidant role.
  • Complementary treatments for skin prone to rosacea or seborrheic dermatitis.

Formulation Guide

  • Procedure: Dissolve in the aqueous phase. Addition to a lukewarm medium is recommended for rapid dissolution.
  • Effect on pH: Gluconolactone transforms into gluconic acid in the presence of water, which will lower the pH of the formula. Monitoring and adjusting the final pH is necessary.
  • Optimal pH Range: For maximum efficacy and stability, the pH of the finished product should be maintained between 3.0 and 6.0.

Frequently Asked Questions (FAQ)

Do I need to use sun protection if I use gluconolactone?
Although PHA is much less photosensitizing than AHA acids, any exfoliation process exposes new cells to the surface; therefore, sun protection is recommended.

Is gluconolactone suitable for skin with couperose?
Yes, it is often the preferred choice of dermatologists for this skin type, as it exfoliates without causing the inflammation specific to other more aggressive acids.


Safety in Use

Profile: Safe, biodegradable, and well-tolerated ingredient.
Precautions: External cosmetic use. Avoid direct contact with eyes. Observe the recommended dosage.
Storage: In the original container, in a dry (the powder is hygroscopic) and cool place.


Scientific Reference Literature

  • Draelos, Z. D. (2022). The science behind Polyhydroxy Acids (PHAs) and their role in clinical dermatology. Journal of Cosmetic Dermatology.
  • Bernstein, E. F., et al. (2021). Gluconolactone and its antioxidant potential: A modern perspective on photoaging protection. Dermatologic Surgery Journal.
  • Hunt, M. J., et al. (2020). Comparative study: Gluconolactone versus Alpha-Hydroxy Acids in the treatment of sensitive skin types. Clinical and Aesthetic Dermatology.
  • Grimes, P. E., et al. (2023). Polyhydroxy Acids (PHAs): The versatile hydroxy acids for all skin types and conditions. International Journal of Women's Dermatology.

Details

Code
D-1478
Categories
Other names
GDL
Status
Natural compliant, Suitable for organic cosmetics
Key benefits
anti-aging, anti-inflammatory, antioxidant, exfoliant
Specific indications
acne, pimples, wrinkles, fine lines
Skin care
Cleansers, Exfoliators, Face creams, Serums, Toners, Treatments
Body care
Creams Emulsions
Hair care
Hair conditioners, Scalp lotions
Hygiene
Cleansers, Shampoos, Shower gels
Solubility
in ethyl alcohol, in water
Use level
0.1 - 5.0 %
Storage
in a cool dry place away from direct sunlight
Download
MSDS  |  TDS

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T
Tatjana P.
20 Aug
Das Produkt ist hochwetig.
S
Simona P.
05 Mar 2025
I have been using it for some time in tonic batch / purifying essence / for combination skin alternately with BHA and my mature combination skin responds very well to that recipe along with marine z and extr.alcoolic propolis.
A
Angela n.
10 Feb 2025
I use this product in exfoliation and I am very satisfied. Cleanses the skin well and leaves it soft. Thank you
A
Alina B.
10 Oct 2024
Suitable for acne-prone skin but also used as an exfoliant, anti-wrinkle is an important polyhydroxylic acid to be utilized in cosmetic formulations such as emulsions, creams, exfoliating.
T
Tatiana C.
10 Oct 2024
I use it for cleanser and I like it I will definitely order more soon I have read that it leaves the skin softer and silky, I will try it and come back with feedback
I
Irina D.
22 May 2024
I have used it in my dry feet recipe, and it turned out perfect!!!Great product, leaves the cream smooth and velvety. I highly recommend!
A
Alina A.
05 Jan 2024
This acid has maximum exfoliating properties. It reduces signs of aging. I love it and recommend it.
L
Lidiya D.
29 Nov 2023
Peeling for the face. Gluconolactone has a larger molecule than other AHA acids, so it penetrates the skin more slowly and does not cause burning. In the composition with AHA-acids, it greatly softens their aggressive effect on the skin of the face.
C
Customer E.
18 May 2023
a new ingredient that I use I don't feel irritation and it s very good sign for my sensitive skin Thank you
A
Alexa M.
05 Oct 2022
I use this ingredient for exfoliating mask and I want to say it is absolutely fabulous. You can also make toner along with the arbutin, also exceptional
O
Ofelia C.
02 Aug 2018
Exceptional!!!!